Where Lampbrush Chromosomes First Found

                                   Lampbrush Chromosomes 

In 1882 Flemming first  observed this type of chromosomes in oocyte of amphibians . In the meiotic prophase stage of diplotene this oocyte is developed  due to active transcription of many genes .  The chromosomes  is consist of two pair of sister chromatids held together by chasmata therefore this are also known as Bivalant structure of meiosis .   Lampbrush chromosomes are easily visible in light microscope where they organised in the form of large extended loops and this loops are surrounded by a matrix of ribonucleotide proteins that contain nascent RNA chains . Lambrush chromosomes are thought to assist in fulfilling the high demand for transcripts during oogenesis .