Where Lampbrush Chromosomes First Found
Lampbrush Chromosomes
In 1882 Flemming first observed this type of chromosomes in oocyte of amphibians . In the meiotic prophase stage of diplotene this oocyte is developed due to active transcription of many genes . The chromosomes is consist of two pair of sister chromatids held together by chasmata therefore this are also known as Bivalant structure of meiosis . Lampbrush chromosomes are easily visible in light microscope where they organised in the form of large extended loops and this loops are surrounded by a matrix of ribonucleotide proteins that contain nascent RNA chains . Lambrush chromosomes are thought to assist in fulfilling the high demand for transcripts during oogenesis .
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