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Showing posts from September 16, 2018

Bruce Ames Contribution In Oncology

                                                                                                       Ames Test  Bruce Ames develops a method to  test the chemicals for cancer causing properties .  The test is based on the fact that  any thing that is mutagenic may also turn out to be a carcinogen, that is to cause cancer . The assay is based on the reversion of the mutation in the histidine operon in the genetically altered tester strains of bacterium Salmonella typhimurium . The his peron encodes enzymes required for the biosynthesis of the amino acid hitsidine . Strains with mutations in the his operon are histidine auxotrophs . However , the mutation can be reversed , a back mutation , with the gene...

Where Lampbrush Chromosomes First Found

                                   Lampbrush Chromosomes  In 1882 Flemming first  observed this type of chromosomes in oocyte of amphibians . In the meiotic prophase stage of diplotene this oocyte is developed  due to active transcription of many genes .  The chromosomes  is consist of two pair of sister chromatids held together by chasmata therefore this are also known as Bivalant structure of meiosis .   Lampbrush chromosomes are easily visible in light microscope where they organised in the form of large extended loops and this loops are surrounded by a matrix of ribonucleotide proteins that contain nascent RNA chains . Lambrush chromosomes are thought to assist in fulfilling the high demand for transcripts during oogenesis .   

Types Of Meiosis in sexually reproducing Individuals

                                    Types of Meiosis  Meiosis and fertilization are two essential processes in the life cycle of sexually reproducing organisms. In every such organism, these two events represent alternating phases that work together to maintain a constant number of chromosomes from one generation to the next. Although the timing of meiosis and fertilization may vary among different species, the fundamental processes remain consistent across all sexually reproducing organisms. Based on the timing and relationship of these events, meiosis can be classified into three types. - Gametic  zygotic  sporogenic  Gametic - Gametic type of meiosis occurs in the formation of gamete which is haploid in nature. The gamete further gives rise to a diploid zygote. This zygote by mitotic division changed into an organism.  This type of division is generally...

Steps Involved in Pisciculture : Biology Blog

                                              What is Pisciculture? Pisciculture is a branch of animal husbandry that deals with the rearing and cultivation of fish in controlled environments such as ponds, tanks, and other enclosures. The term comes from the Latin words "piscis" , meaning fish, and "culture" , meaning to cultivate or rear. Pisciculture is a major part of aquaculture , which includes the farming of other aquatic organisms like prawns, mollusks, and aquatic plants. Today, pisciculture has become an important source of income and nutrition, especially in countries with access to freshwater and coastal resources. Why is Pisciculture Important? Fish and fish products are considered some of the healthiest sources of animal protein . They are rich in omega-3 fatty acids, vitamins (like D and B2), and essential minerals (like calcium and phosphorus). With i...

Gram Positive , Gram Negative Bacteria With Staining method

                     Gram-Positive Bacteria & Gram-Negative   Bacteria have a cell wall made up of polysaccharides known as Peptidoglycans which gave them strength and rigidity and this is important since bacteria observe some osmotic pressure due to the variation of different solutions they encounter and their cell wall which prevents the cell from shrinking or swelling. So , on the basis of the cell wall and the pattern of gram staining, bacteria are classified into two categories - Gram-Positive and Gram-Negative. Gram-positive bacteria  have double-thick walls which consist of around 30 layers of peptidoglycan and surrounds a single plasma membrane.  They do not have an outer cell membrane but have a complex cell wall made up of teichoic acid.  For example - Staphylococci.   Gram-negative bacteria  have a much thinner cell wall consisting of peptidoglycans having high lipid content...