convolascent plasma therapy for cornonavirus

Hello guys!

 The elevating cases of corona in the world forced researchers to discover antibiotics.  scientists experimenting and researching continuously to develop vaccines or therapy that may help to beat the corona crisis.

So, one of the therapies that doctors believe to experiment on patients is plasma therapy. Plasma is a watery fluid of the blood. This plasma is consists of corpuscles and thrombocytes in addition to that plasma also contains some proteins (immunoglobulin) which produce antibodies.
Our body works on the principle of the immune system. The basic principle of the immune system is that it forms antibodies against any foreign antigen that enters the body. Our immune system memorizes this antigen and this is called the primary response. If the second time again this same antigen comes into the body by any means then our antibody recognizes it and neutralizes this foreign antigen.  This principle is becoming helpful for experimenting against coronavirus.

If any person recovered from this virus then the plasma of that person can be used to fight against this virus. These antibodies can be used to treat more patients who are suffering from this virus. The antibody memorizes this foreign antigen and neutralizes the virus. In this way, we could save multiple person' life suffered from covid-19.

Related Links  - Things to know about coronavirus 

                           Impact of coronavirus on mental health 

    

Past history of this therapy - 

• This therapy is recommended by the WHO in treating the Ebola virus.
• In 2015, this therapy is used in treating middle East respiratory disease which is also caused due to coronavirus
• At the time of the Spanish flu, this therapy was used experimentally.
• At the time of SARS, this therapy showed a good effect. 

Plasma therapy in present - Convalescent plasma therapy is explored by China and try it on some patients and they revealed that the patient showing improvement in recovery was noticed and all of them later on discharged. This exploration was published by China in the Journal of American Medical Association. 

However, this process in under trial as the research utters that there is some unknown right that needs to resolve out like in what quantity doses will work as antibodies? At what stage of illness it will be given to the patient? Are some reasons that will need to be addressed.

Things to know about pandemic disease coronavirus : Biology Blog

                                        Coronavirus

Coronavirus is an infectious disease that is spreading rapidly all over the world. More than 20 lakh people of the world have been affected by this virus and incoming time its chances of increase will be more. It is coming from the Wuhan, the capital of China on 29 December 2019 and since then it is spreading more fastly.

Symptoms - Fever, cold, cough, fatigue, diarrhea are general symptoms of this virus.  Older people and the child under 10 years of age are prone to this pandemic disease. The symptoms of this disease will appear between two to fourteen days. The people having a pre-existing disease like cancer, respiratory problems and diabetes have more risk to get the infection.

Mode of transmission - This virus is inactive until they do not get any host body to replicate their genome. After entering into the host body they first attach to the respiratory system and block the system, a consequence of that person feel some cough problem. The virus lives here for some days and multiplies their copy and after that slowly affects the whole body and then the person feels muscular pain and then fever is resulted out.

Its mode of transmission is just similar to the normal flu. If any normal person comes in contact with the affected one then this virus jumps into that person and in results, the person develops symptoms. 

Similarly, if the person touches the contaminated surface and then touches their mouth, nose, and ear then this virus gets its way to enter into mouth. This virus is active on the surface up to 72 hrs.
Have you read- Impact of coronavirus on mental health  of people 

Preventive measures to adopt - 

• Always use the mask to cover your mouth and nose area.
• Avoid close contact with the affected person.
• If for any reason or unknowingly you come in contact with the person having symptoms then isolate yourself for a minimum of 14 days.
• Follow social distancing.
• Stay at home.
• Regular drink warm water at least once in a day.
• Wash your hands with soaps at least 20 times a day.
• Use sanitizer.

Explain transgenic animals and ethical issues : Biology Blog

                             Transgenic Animals & ethical issues 

Hello guys!

on this blog, we are going to discuss what are the transgenic animals and what are the issues related to that. So, guys, transgenic animals are those animals that have their DNA  manipulated so that the extra foreign gene can be expressed. There are multiple examples of transgenic animals like sheep, cows, mice, rats, etc.

Reasons for developing transgenic animals -  

• To the understanding of gene regulation and their effect on normal physiology of the animal and its development. For example, we can study various growth factors.
• The study of the disease can be done by studying genes, which are responsible for causing disease in human and their treatments.
• Biological products can be produced by introducing the portion of DNA, which codes for a particular product into transgenic animals. For example - human protein ( alpha-antitrypsin ) is used to treat emphysema.
• Rosie, the first transgenic cow was produced in 1997 for the purpose of producing protein-enriched milk. This milk contain the human alpha - lactoalbumin and was nutritionally balanced for human babies.
  
• For testing vaccine.
• For testing chemical safety transgenic animals are required.

Method representation -

Ethical issues -

• When this type of organism is exposed to the environment , there are chances of unpredictable results.
• The modification/usage of living organisms for public service has also created problems with patents granted for the same.
• In order to control these issues. the Indian government has set up an organisation such as GEAC, which makes a decision regarding the validity of genetically modified research and the safety of introducing GM organisms for public services.