Frederick Griffith transformation experiment and conclusion

Griffith Experiment

Introduction -

1918 is the year of pandemic Influenza, the disease that was spread on a large scale over worldwide and killed a large population of the world. Influenza disease is that which spread through animals into a human. The scientist was studying the possibility of a vaccine for Influenza. In 1928 Fredrick Griffith's success in discovering the vaccine for neutralizing the virus.

Experiment -

Fredrick Griffith had done the experiment for this. He conducted his experiment by using two strains of streptococcus bacteria; one is type III -S (smooth ) which is virulent and type II -R (rough) which is non-virulent. Type III- S has capable of forming a capsule made up of sugar (polysaccharide) that helps to protect from the host immune system consequently the death of the host. Type II -R is not able to form a coating around the body and affected by the host immunity resulting in no death of the host.

Also, refer- Griffith experiment in Hindi

The whole experiment can be well understood by the figure -

Conclusion - By doing his experiment he concluded that bacteria are capable of transforming genetic information by following the principle of transformation which can change them from one form to another form.

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