Hemophilia - A Genetic Disorder : Biology Blog

-

                                        Hemophilia






With haemophilia, a hereditary condition, blood continues to ooze after a minor injury, a seizure, or even after you pull out your tooth. This happens as a result of the body's lack of a blood clotting factor. Internal bleeding that affects the body's major organs, such as the brain, muscles, or joints, can occasionally occur. This type of bleeding is more serious.

When we are harmed, our blood typically oozes out for a while before coagulation forms to prevent more bleeding. This is made possible by the body's 8th and 9th blood clotting factors, which regulate bleeding. If these factors are missing or absent, this condition develops.

Symptoms- The symptoms of this disease may vary depending upon the level of the clotting factor.
    Types Of hemophilia - There are two types of hemophilia - hemophilia A and hemophilia B.

        The gene F8, which also gives instructions for producing blood clotting factor 8, is absent or mutated in haemophilia A, which leads to the disease. Haemophilia B is brought on by mutations in gene 9 that provide instructions for producing blood clotting factor 9th later ( also known as Christmas factor ). Together, these two genes support the blood clotting process.



Inheritance pattern - The problematic gene is frequently found on the X chromosomes in common situations. We are aware that each person inherits one set of sex chromosomes from their father and mother. Males inherit one X and one Y chromosome from their parents, respectively. The mother gave each female one chromosome, while the father gave each female an X chromosome.

This indicates that this illness only affects men and is always passed from mother to son. Women act as the disease's carriers.

Risk Factor - family history is the biggest risk factor for the inheritance of this disease.

Acquired Haemophilia - Although 30% of people with haemophilia do not have a family history of the condition, the ailment typically develops as a result of pattern inheritance.
A uncommon illness called acquired haemophilia causes the body's autoimmune system to become active and kill the cells that produce blood clotting factors. It may be related to multiple sclerosis, cancer, or pregnancy.
  

Comments

Post a Comment

Popular posts from this blog

Sycon Canal System With Diagram & Significance | Biology Blog

-
Image
                                     Canal system in Sycon  A sea creature called a sycon, or scypha , is usually found clinging to rocks or other surfaces. These creatures have tube-shaped bodies that open outward with the help of a hole called an Osculum . They have tiny openings called Spiracles and Ostia all over their bodies to let water in. This water flows through canals inside their bodies and comes out through the Osculum, which is a larger opening used for breathing. We'll observe the shape of this canal system, why it is essential for those animals, type of canal system , and  its significance. The Sycon Type Canal system is the unique feature of the phylum Porifera . This system is also known as the  aquiferous canal system . This system supports the significant function of the body like nutrition, respiration, excretion, etc. History Overview -  Grant, a scientist from Scotland, spent a lot of time studying sponges. He was one of the first to really explain how t
Read more

Aurelia Aurita Life Cycle: Characterstics, Classification

-
Image
                                             Aurelia  Aurelia aurita is a type of zooplankton found all over the world. They are see-through and don't have eyes, brains, or hearts. They're usually between 2 to 15 inches wide. Even though they prefer being alone, they get carried together in groups called Blooms by wind and water currents. At night, they look like they're moving through the water like jellyfish, which is why they're sometimes called " jellyfish ".  They have four reproductive organs surrounded by tentacles in their top part. Their body color changes based on what they eat, so they can be blue, pink, or other colors. Let's learn more about Aurelia in detail. Details Of Aurelia Diagram -  Body : The center of the diagram would display the jellyfish's bell-shaped body, often called the " umbrella. " Tentacles : Below the bell, you'd see long, hair-like tentacles extending outward. Oral Arms : The oral arms are  used for
Read more

Types of Eggs of Animals in Zoology (Embryology ) | Biology Blog

-
Image
                                             Types of Egg Hello guys! We'll examine a crucial area of zoology in this blog: different varieties of eggs. So let's define reproduction first before moving on to the subject. Reproduction is the biological process in which a parent is responsible to produce their offsprings which may be of their own kind. Reproduction is a must process for every individual for the continuing existence of the species. As we all know, there are many different species on the planet, and each of them has a unique method of egg production and inside the egg they contain yolk . The yolk is composed of proteins, fats, vitamins, and minerals, which are vital for the growth and development of the embryo.  Eggs can be classified into different types based on the amount of yolk they contain. l.  On the basis of the amount of Yolk - Depending on the quantity of yolks, eggs can be  Alecithal / Microlecithal / oligolecithal - The amount of yolk pr
Read more